22 is the deuteragonist of the Pixar film Soul. After Joe Gardener arrived to the Great Before after an accident which led to the failure of Joe entering the great beyond, 22 is tasked to help Joe get back to his body before it's too late.
22 is a rebellious soul in the "great before", an unknown location also known as the "You Seminar". 22 was considered to be the 22nd soul in the universe, but refused to enter a human body. Unlike most souls, 22 is completely unable to find her "Spark", an idea that allows a soul to go through to Earth to be born into a human body.