Mrs. Potato Head is the female counterpart to Mr. Potato Head. Although only mentioned at the end of Toy Story as Molly's Christmas present, she makes her first real appearance in Toy Story 2 as Mr. Potato Head's wife. After learning that her husband saved the lives of three Squeeze Toy Aliens, she decided to adopt them.
In Toy Story 3, Mrs. Potato Head appears to be missing one of her eyes (possibly because it had gotten lost or missing some time after Toy Story 2).